Thank you for writing.

I think that the fundamental error Dr. Bossche is making is that he believes that a partially vaccinated population would select for variants that would bypass the vaccine.

Though it is likely that if a vaccine evasive variant arises, it will prey selectively on the pool of vaccinated persons preferentially and thus become more dominant, in pandemic, the rise of new variants is more dominantly a function of how many persons are naturally infected. Every infected person is the potential factory where the next new variant could arise.

Fundamentally, I think that Dr. Bossche is vastly over-estimating the importance of the "selective pressure" the population of vaccinated people will exert in creating "vaccine bypass".

Also, so what if the vaccine immunity is bypassed eventually, this is what we deal with annually with the Flu. Once the SARS-CoV-2 virus drops to endemic levels we can adjust vaccine sequences, as we do with the Flu.

The bottom line is that sheer number of persons susceptible to infection and serving as factories for new viral polymorphisms, far outweighs any selective pressure exert by a single vaccine. In a setting where the current vaccine can and do protect against infection by the vast majority of the dominant variants in circulation.

Following Dr. Bossche's suggestion to abandon vaccinations will, therfore, not only lead to a higher mortality in the near term, it will also lead to the generation of vast array of new variants from billions of infected people that would only become an impenetrable repertoire of virulent Coronaviruses.

Bossche's idea is dangerous and not well thought out.

I hope this explanation helps you.